所在部门/单位：材料科学与工程学院

办公电话：15705957796

Email：cuizhixiang2006@126.com

实验室介绍

组织工程支架是种植细胞的场所和组织再生的模板。如何制备理想的多孔生物支架，在组织工程领域引起了越来越多的关注。本实验室旨在针对生物材料在组织工程领域的应用，采用各种新技术、新原理，解决生物支架中的关键性问题，为实现生物支架的高性能化提供新途径、新方法。该方向的主要研究领域包括：1.组织工程支架高性能化新技术和新原理；2.组织工程支架表面结构开发；3.组织工程支架的仿生制备；4.纳米复合组织工程支架的制备。

教育背景

2006.09—2012.07郑州大学材料科学与工程学院材料加工工程博士

2009.09—2011.10美国威斯康辛麦迪逊大学机械工程学院机械工程联陪博士

2000.09—2004.07郑州轻工业学院高分子科学与工程系高分子科学与工程学士

工作经历

2015.07—福建工程学院材料科学与工程学院， 副教授

2012.09—2015.06福建工程学院材料科学与工程学院， 讲师

组织工程支架研发及应用；纳米复合材料制备；生物高分子表面改性

主要科研项目

1.2016.03-2019.02以充氮气替代六氟化硫的环保型气体绝缘12kV用负荷开关开发与应用福建省高校产学合作科技重大项目 40万 主持.

2.2016.09-2019.08静电纺丝制备高分子复合纤维组织工程支架 福建省高校杰出青年科研人才计划5万主持.

3. 2016.01-2017.11三维多孔生物支架制备及其生物矿化研究 国家级重点实验室联合开放课题5万主持.

4.2014.01-2016.12 具有微管道的三维组织工程支架VARTM制备及性能研究国家自然科学基金25万主持.

5.2014.09-2016.12 三维多孔组织工程支架微孔结构调控及性能研究中国博士后科学基金委 8万主持.

6.2014.12-2017.11高分子纳米纤维药物释放系统的制备及释药机理研究 福建省高校科研专项 5万主持.

论文

1. Zeng S., Cui Z. X.*, Yang Z. Q. et al. Characterization of highly interconnected porous poly(lactic acid) and chitosan-coated poly(lactic acid) scaffold fabricated by vacuum-assisted resin transfer molding and particle leaching [J]. Journal of Materials Science. 2016, 51(22): 9958-9970.

2. Si J. H., Cui Z. X.*, Liu C. T. et al. Characterization of 3D elastic porous polydimethylsiloxane (PDMS) cell scaffolds fabricated by VARTM and particle leaching [J]. Journal of Applied Polymer Science. 2016, 1(1): 42909-42918.

3. Si J. H., Cui Z. X.*, Wang Q. T. et al. Biomimetic composite scaffolds based on mineralization of hydroxyapatite on electrospun poly(caprolactone)/nanocellulose fibers [J]. Carbohydrate Polymer. 2016, 143C:270-278.

4. Cui Z. X., Si J. H., Liu C. T. et al. Flowing simulation of injection molded parts with micro-channel [J]. Applied Mathematics and Mechanics (English Edition). 2014, 35(3): 269-276.

5. Cui Z. X., Zhao H. B., Peng Y. Y. et al. Fabrication of highly porous interconnected three-dimensional scaffold with micro-channels [J]. Chinese Journal of Polymer Science. 2014, 32(7): 1-7.

6. Cui Z. X., Zhao H. B., Peng Y. Y. et al. Fabrication and Characterization of Highly Porous Chitosan/ Poly(DL-lactic-co-glycolic acid) Nanocomposite Scaffolds Using Electrospinning and Freeze Drying [J]. Journal of Biobased Materials and Bioenergy. 2014, 8(3): 281-291.

7. Cui Z. X., Peng Y. Y., Li K. et al. The degradation rate of polyanhydride (poly(sebacic acid), diacetoxy terminated, PSADT) [J]. Journal Wuhan University of Technology, Materials Science Edition, 2013, 28(4): 793-797.

8. Cui Z. X., Peng Y. Y., Liu C. T. et al. Flow analysis of injection-molded parts with cylindrical microfeatures. Proceedings of the Institution of Mechanical Engineers, Part C [J], Journal of Mechanical Engineering Science. 2012, 226: 1612-1619.

9. Cui Z. X., Zhao H. B., Peng Y. Y. et al. Morphology and properties of porous and interconnected poly(e- caprolactone) matrices using solid and microcellular injection molding [J]. Journal of Biobased Materials and Bioenergy. 2012, 6(3): 259-268.

10. Cui Z. X., Nelson B., Peng Y. Y. et al. Fabrication and characterization of injection molded poly (epsilon-caprolactone) and poly (epsilon-caprolactone)/hydroxyapatite scaffolds for tissue engineering [J]. Material science and engineering C. 2012, 32(6): 1674-1681.

11.Cui Z. X., Zhao H. B., Peng Y. Y. et al. Study of Moprhology of Microcellular Injection Molded Scaffolds for Tissue Engineering [C]. ANTEC, April 21-24, 2013, Ohio, Presentation.

12. Cui Z. X., Zhao H. B., Peng Y. Y. et al. Fabrication of highly tubular porous chitosan/poly(DL-lactic-co-glycolic acid) (PLGA) nanocomposite structures intended for tissue engineering scaffold applications [C]. ANTEC, April 2-4, 2012, Orlando, Presentation.

13. Cui Z. X., Peng Y. Y. Turng L-S. Analysis of morphology on injection molded poly(ε-caprolactone) tissue engineering scaffolds [C]. ANTEC, May 1-5, 2011, Boston, Presentation.

14. Cui Z. X., Peng Y. Y., Li K. et al. Study on the degradation rate of polyanhydride (poly(sebacic acid), diacetoxy terminated, PSADT) for potential drug delivery and tissue engineering scaffold applications [C]. ANTEC, May 1-5, 2011, Boston, Presentation.

15. Zhao H. B., Cui Z. X. Sun X. F. et al. Morphology and Properties of Injection Molded Solid and Microcellular Polylactic Acid/Polyhydroxybutyrate-Valerate (PLA/PHBV) Blends [J]. Industrial & Engineering Chemistry Research. 2013, 52(7): 2569-2581.

16. Zhao H. B., Cui Z. X. Sun X. F. et al. Processing and characterization of solid and microcellular poly(lactic acid)/polyhydroxybutyrate(PLA/PHBV) blends and PLA/PHBV/Clay nanocomposites [J]. Composites Part B: Engineering. 2013, 51: 79-91.

17. Li K., Cui Z. X. Turng L-S. The effect of nanoclay on the morphology and properties of injection-molded solid and microcellular Polyactide/ poly (butylene adipate-co-terephthalate) blends [J]. Journal of Biobased Materials and Bioenergy. 2011, 5: 442-451.

专著/译著

崔志香. 生物可降解组织工程支架的成型及结构性能[M], 北京:国防工业出版社，2015.

专利等

1.2016 一种高模量超亲水生物支架制备方法发明专利201610569380.X排名第一.

2.2016 一种静电纺丝装置实用新型 201610569503.X 排名第一.

3.2016一种高孔隙率高连通性生物支架制备方法发明专利201610569584.3排名第一.

4.2016一种静电纺丝装置 发明专利201620760993.7 排名第一.

获奖情况

2014三维多孔PCL生物支架制备及性能研究第十一届福建省自然科学优秀学术论文二等奖排名第一.