Polymers synthesized by molecular imprinting technology are commonly known as molecularly imprinted polymers (MIP). In this work, nanoparticles of MIP for beta-caryophyllene (NP-MIP-beta CP) were synthesized and incorporated into poly (epsilon-caprolactone) PCL fibers by electrospinning, where morphological characterization was performed by SEM and average diameter of 129 +/- 32.3 nm was found. Also, PCL electrospun fiber diameters without and with nanoparticles were 1.66 +/- 1.12 and 0.70 +/- 0.24 mm, respectively. Chemical characterization by infrared spectroscopy (FTIR) confirmed the synthesis of the NP-MIP-beta CP and vibrational band present at 1628 cm(-1) indicates the insertion of the NP-MIP-beta CP into PCL fibers. It was found the influence of the incorporation of NP-MIP-beta CP in thermal and tensile properties of the PCL electrospun membrane. Therefore, NP-MIP-beta CP can be incorporated in PCL electrospun membranes by electrospinning and presents a potential application in the pharmaceutical and biomedicine areas, and biosensors. (C) 2020 Elsevier B.V. All rights reserved.