Polyimides form an important class of high-performance polymers. Polyamides with aromatic macromolecular architecture have revealed excellent conducting, mechanical, and thermal properties for aerospace, automotive, electronics, and other technical industries. Recently, polyimide nanofiber and polyimide nanocomposite nanofiber have been focused for fabrication, essential physical features, and subsequent performance. Due to diversity of dianhydrides, diamines, and reinforced nanoparticles, various polyimide nanocomposite nanofibers have been judiciously designed. This comprehensive review highlights indispensable perspectives of polyimide nanocomposite nanofiber particularly polyimide/graphene, polyimide/carbon nanotube, and polyimide/inorganic nanoparticle-based nanofibers. It is envisioned that nanocomposite nanofibers have various high-value applications such as membranes, battery separators, electrodes, etc.