Polyacrylonitrile (PAN) nanofibers were obtained by electrospinning technique prior to surface modification with polyethylenediaminetetraacetic acid (EDTA) using ethylenediamine (EDA) as the cross-linker. The modified nanofibers (EDTA-EDA-PAN) were subsequently applied in the wastewater treatment for the removal of Cd(II) and Cr(VI). Textural and chemical characterizations of the nanofibers were carried out by analysis of the specific surface area (Brauner Emmet and Teller (BET)) and thermogravimetric analyses, scanning electron microscopy and Fourier transform infrared spectroscopy. From the adsorption equilibrium studies with Langmuir, Freundlich and Temkin isotherm models, Freundlich was found most suitable for describing the removal mechanism of the target metals as they collect on a heterogeneously functionalized polymer surface. The EDTA-EDA-PAN nanofibers showed effective sorption affinity for both Cd(II) and Cr(VI), achieving maximum adsorption capacities of 32.68 and 66.24 mg g(-1), respectively, at 298 K. In furtherance, the nanofibers were regenerated by simple washing with 2 M HCl solution. Conclusively, the EDTA-EDA-PAN nanofibers were found to be efficient for the removal of Cd(II) and Cr(VI) in water effluents. (C) 2016 Elsevier B.V. All rights reserved.