400-8910-119
首页 > 文献资料 > ES-Bank > 详情
Fabrication of PLGA nanofibers on PDMS micropillars for neuron culture studies
2019/11/27 21:22:35 admin
We fabricated a nanocomposite substrate made of nanofibers on micropillar arrays by photolithography, soft lithography and electrospinning for cell culture studies. This nanocomposite substrate combines the advantage of the extra-cellular matrix (ECM)-like surface morphology and high porosity and low stiffness of underneath supporting material. For neuronal culture studies, we used nanofibers of poly (lactic-co-glycolic acid) (PLGA) on high aspect ratio micropillars of polydimethylsiloxane (PDMS). Our results showed that primary hippocampal neurons on such a nanocomposite substrate have different cell morphology than on flat surfaces and they showed more electric activities. Thus, the nanofiber-micropillar composite substrates were shown to be useful for neuron culture studies. (C) 2017 Published by Elsevier B.V.
相关推荐
暂无相关推荐
网友评论 请遵循相关法律法规,理性发言
回复
查看更多回复

分享