Indium Tin Oxide (ITO) nanofibers; were fabricated by the electrospinning process. Sensors based on these nanofibers were fabricated by applying silver paste as electrode. The morphology and crystal structure of ITO nanofibers were studied by Scanning Electron Microscopy (SEM) and X-ray diffraction (XRD), respectively. The optimal working temperature and sensor response of ITO nanofiber sensors were investigated. All results showed that ITO nanofiber sensors have good sensor response for NO(2) at temperatures as low as 50 degrees C. (C) 2009 Elsevier B.V. All rights reserved.