Chitosan nanofibers from an easily electrospinnable UHMWPEO-doped chitosan solution system-易丝帮

Chitosan nanofibers from an easily electrospinnable UHMWPEO-doped chitosan solution system

2019/11/27 21:19:57 Zhang, Y. Z., B. Su, S. Ramakrishna and C. T. Lim

Conversion of natural biopolymer chitosan into nanofibers through electrospinning has significant usefulness in various biomedical applications, in particular, for constructing a biomimetic and bioactive nanofibrous artificial extracellular matrix for engineering various tissues. Here, we show that introduction of an ultrahigh-molecular-weight poly(ethylene oxide) (UHMWPEO) into aqueous chitosan solutions remarkably enhances the formation of chitosan nanofibrous structure and leads to much lower loading of the water soluble fiber-forming aiding agent of PEO down to 5 wt % as compared to previous high PEO loadings in the electrospun chitosan nanofibers. The excellent electrospinnability of the current formulation renders electrospinning of natural biopolymer chitosan a robust process for large-scale production of practically applicable nanofibrous structures.

Journal: Biomacromolecules
Volume: 9
Issue: 1
Pages: 136-141
ISSN: 1525-7797
DOI: 10.1021/bm701130e
Year: 2008
Number:
Type:

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