Preparation and characterization of a novel electrospun spider silk fibroin/poly(D,L-lactide) composite fiber
2019/11/27 21:19:26
Zhou, S. B., H. S. Peng, X. J. Yu, X. T. Zheng, W. G. Cui, Z. R. Zhang, X. H. Li, J. X. Wang, J. Weng, W. X. Jia and F. Li
In the paper, we successfully prepared spider silk fibroins (Ss)/poly(D,L-lactide) (PDLLA) composite fibrous nonwoven mats for the first time to the best of our knowledge. The morphology of the fibers was observed by a scanning electron microscope (SEM) and transmission electron microscope (TEM). The secondary structure change of the spidroin before and after electrospinning was characterized using Fourier transform infrared spectroscopy (FT-IR). Herein, a qualitative analysis of the conformational changes of the silk protein was performed by analyzing the FT-IR second-derivative spectra, from which quantitative information was obtained via the deconvolution of the amide I band. A mechanical test was carried out to investigate the tensile strength and the elongation at break. A water contact angle (CA) measurement was also performed to characterize Surface properties of the fibers. The cytotoxicity of electrospun PDLLA and Ss-PDLLA nonwoven fibrous mats was evaluated based on a CCL 81(Vero) cells proliferation study. The results showed that the hydrophilic and mechanical property of the composite fiber were improved by introducing spidroin.
- Journal: Journal Of Physical Chemistry B
- Volume: 112
- Issue: 36
- Pages: 11209-11216
- ISSN: 1520-6106
- DOI: 10.1021/jp800913k
- Year: 2008
- Number:
- Type:
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