A facile approach to prepare shell/core nanofibers for drug controlled release-易丝帮

A facile approach to prepare shell/core nanofibers for drug controlled release

2019/11/27 21:19:15 Zhu, T. H., C. Y. Yang, S. H. Chen, W. Y. Li, J. Z. Lou and J. H. Wang

Model drug-loaded coaxial electrospun PVP@nano-biopolymers core-shell composite nanofibers were fabricated by a facile coaxial electrospinning successfully. The model drug FA, which is a kind of lipid microsphere non-steroidal anti-inflammatory drug, was shown to be successfully adsorbed in the PVP, and the formed FA/PVP/biopolymers composite nanofibers exhibit a uniform and smooth morphology. The loaded FA within the PVP/biopolymers coaxial nanofibers showed a sustained release profile. With the significantly reduced burst-release profile, the developed FA/PVP/biopolymers composite nanofibers were proposed to be a promising material in the fields of pharmaceutical science. (C) 2015 Elsevier B.V. All rights reserved.

Journal: Materials Letters
Volume: 150
Issue:
Pages: 52-54
ISSN: 0167-577X
DOI: 10.1016/j.matlet.2015.02.120
Year: 2015
Number:
Type:

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